EFFECTS OF Maytenus senegalensis (L) AND Cassia alata (L) EXTRACTS ON THE BLOOD PARAMETERS OF ALBINO RATS INFECTED WITH Schistosomes cercariae
Keywords:
Maytenus senegalensis; Cassia alata; Blood parameters; Rat; Schistosomes cercariaeAbstract
An investigation was carried out to assess the effects of the roots, leaves and stem-bark of
Maytenus senegalensis and the seed and leaves of Cassia alata extracts of methanol and aqueous
water at 3, 6 and 9g/kg body weight on the blood parameters of albino rats previously infected
with schistosome cercariae using the Danish Bilharzias’ Laboratory method. The results showed
that the aqueous water 3g/kg and 6g/kg body weight extracts of the leaves with values of 12.8 x
103μ/l and 15.7 x 103μ/l of white blood cells respectively were above the normal values of (0.96
– 11.06 x 103μ/). Other values of Maytenus senegalensis and those of Cassia alata of blood
parameters remain within the normal values. It was observed that these water extracts increased
the white blood cell count. Therefore the utilization of water extract in the treatment is not
recommended.