ANTIBIOTIC SUSCEPTIBILITY PATTERNS OF ESCHERICHIA COLI AND STAPHYLOCOCCUS AUREUS ISOLATED FROM URINE OF DIABETIC AND NONDIABETIC PATIENTS IN KADUNA TOWN

Abstract

The isolation of Escherichia coli and Staphylococcus aureus was carried out from the urine of diabetic and non-diabetic patients attending Sabon Tasha General Hospital, Gwamna Awan General Hospital, and Yusuf Dantsoho Memorial Hospital located in Kaduna Town. Eosin Methylene Blue Agar was used for the isolation of E. coli while Mannitol Salt Agar was used for the isolation of S. aureus. The patterns of the antibiotic susceptibility were determined using standard methods and antibiotics discs obtained from Maxi Care Medical, Lagos, Nigeria. The results obtained revealed that the isolated S. aureus had the highest percentages of 62.9% and 64.3% in the urine samples of diabetic and non-diabetic patients respectively. S.aureus had the highest mean zone diameter of inhibitions (mm) of 25±2.89 for Streptomycin
while E. coli had 19.5±4.13 for Ciprofloxacin. The P values obtained, which were all ≥ 0.05 showed that there were no significant differences in the bacterial prevalence results obtained for diabetic and non-diabetic patients from the three hospitals. The study showed that S. aureus and E. coli were isolated from the urine samples of both diabetic and non diabetic patients while good hand washing and other hygienic practices should be encouraged by both diabetic and non-diabetic patients to prevent the spread of urinary tract infections.