ISOLATION OF β-SITOSTEROL AND LUPENONE FROM THE METHANOL ROOT EXTRACT OF Cassia sieberiana DC (Fabaceae)

Authors

  • IBRAHIM, J. S. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria- Nigeria.
  • MUHAMMAD, S. Department of Applied Sciences, ShehuIdris College of Health Science and Technology, Makarfi-Kaduna.
  • ATIKU, I. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria- Nigeria.
  • ABDULLAHI, S.M. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria- Nigeria.
  • ILYAS, M. Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria- Nigeria.
  • ISYAKA, M. S. Department of Chemical Science, Faculty of Science, Federal University Kashere-Nigeria.
  • SANI, Y.M Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria- Nigeria.

Keywords:

Cassia sieberiana, β-sitosterol, lupenone, 1D and 2D NMR.

Abstract

Cassia sieberiana DC (Fabaceae) is a small tree with wide spread in India and tropical Africa.
The plant is used ethnomedicinally in African for the treatment of malaria, inflammations and
other infectious diseases. Some of the pharmacological activities of the plant include
antispasmodic, anti-inflammatory and antimicrobial activities.β-sitosterol and lupenone were
isolated by a combination of column chromatography and gel filtration of ethylacetate fraction of
the methanol root extract of the plant. The structures of the compounds were determined by
analysis of their UV, IR, 1D and 2D NMR spectra as well as comparison with the literature data.
This is the first report for the isolation of these compounds from the plant.
Keywords: 

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Published

2020-12-13

How to Cite

IBRAHIM, J. S., MUHAMMAD, S., ATIKU, I., ABDULLAHI, S.M., ILYAS, M., ISYAKA, M. S., & SANI, Y.M. (2020). ISOLATION OF β-SITOSTEROL AND LUPENONE FROM THE METHANOL ROOT EXTRACT OF Cassia sieberiana DC (Fabaceae). BIMA JOURNAL OF SCIENCE AND TECHNOLOGY (2536-6041), 4(02), 102-107. Retrieved from https://journals.gjbeacademia.com/index.php/bimajst/article/view/212

Issue

Vol. 4 No. 02 (2020): Vol. 4 No. 2 December 2020

Section

Articles