ISOLATION OF TARAXASTEROL AND STIGMASTEROL FROM THE AERIAL PART OF Centaurea perrottetii DC. (Asteraceae)

Authors

  • O.G. ADUKU Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • S.M. ABDULLAHI Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • M.I. SULE Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • I. ATIKU Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
  • J.V. ANYAM Department of Chemistry, Federal University of Agriculture, Makurdi, Nigeria

Keywords:

Asteraceae, triterpenes, steroids, NMR spectroscopy, taraxasterol, stigmasterol.

Abstract

Centaurea perrottetii is a well-known plant used in African traditional medicine for its wound
healing, anti-inflammatory, anti-microbial, anti-oxidant as well as cytotoxic properties.
Preliminary phytochemical screenings of the methanol extract of the aerial partof Centaurea
perrottetii revealed the presence of triterpenes, flavonoids, steroids, tannins, saponins and
carbohydrates. Extensive phytochemical investigation of the n-hexane fraction led to the
isolation of a pentacyclic triterpenoid (taraxasterol) and a steroid (stigmasterol). The isolated
compounds were characterised on the basis of spectral data obtained from IR, 1D,2D 1H- and
13C-NMRspectroscopy and comparison withreported literature data.To the best of our literature
search, this is the first report of isolation of taraxasterol and stigmasterol from Centaurea
perrottetii.

Downloads

Published

2020-12-13

How to Cite

O.G. ADUKU, S.M. ABDULLAHI, M.I. SULE, I. ATIKU, & J.V. ANYAM. (2020). ISOLATION OF TARAXASTEROL AND STIGMASTEROL FROM THE AERIAL PART OF Centaurea perrottetii DC. (Asteraceae). BIMA JOURNAL OF SCIENCE AND TECHNOLOGY (2536-6041), 4(02), 86-93. Retrieved from https://journals.gjbeacademia.com/index.php/bimajst/article/view/210

Issue

Vol. 4 No. 02 (2020): Vol. 4 No. 2 December 2020

Section

Articles