Current Trends In Antimalarial Drug Resistance In Nigeria: A Mini Review

Authors

  • Rita Ayanbolade Olowe Research Ethics Unit, UNIOSUN Teaching Hospital UTH, Osogbo, Osun State, Nigeria
  • Otutu Olawumi Department of Medical Microbiology and Parasitology.. College of Health Sciences, P.M.B. 4000. Ogbomoso, Oyo State
  • Ajayi Yewande O Department of Medical Microbiology and Parasitology.. College of Health Sciences, P.M.B. 4000. Ogbomoso, Oyo State
  • Olowe O Adekunle National Agency for Food and drug administration and control (NAFDAC), Nigeria

DOI:

https://doi.org/10.56892/bima.v8i3.775

Keywords:

Antimalarial drug resistance, Plasmodium falciparum, artemisinin-based combination therapies, malaria control, Nigeria

Abstract

The study aimed to review the current trend in antimalarial drug resistance in Nigeria. Methods: We developed and conducted an exhaustive search strategy on PubMed, online Search Engines, and Google Scholar to find scientific articles reporting antimalarial drug resistance in Nigeria. The highest global malaria burden is in Nigeria, a nation with significant antimalarial drug resistance. This paper examines the most recent advancements, challenges, and prospects for addressing the urgent issue of antimalarial drug resistance in Nigeria. The primary objective of this work is to investigate the emergence and spread of resistance to antimalarial drugs, specifically artemisinin-based combination therapies (ACTs). Furthermore, it examines the factors that lead to this resistance, including medication pressure, vector resistance, and health system issues. According to the research, practical measures to address malaria medicine resistance include public health education campaigns, robust monitoring and surveillance systems, and regular reassessment of drug policy.

Moreover, the report explores prospective areas of concentration for future research, such as developing novel antimalarial medications, exploring alternative treatment modalities, and strengthening collaborations on an international level. According to the findings of this review, policymakers, healthcare professionals, researchers, and communities in Nigeria must collaborate in a comprehensive and empirically supported approach to address the issue of antimalarial drug resistance. In order to maintain the efficacy of antimalarial drugs and prevent the development of resistance, urgent action is necessary to address malaria in Nigeria and globally.

 

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Published

2024-09-20

How to Cite

Ayanbolade Olowe, R. ., Olawumi, O. ., Yewande O , A. ., & Adekunle, O. O. . (2024). Current Trends In Antimalarial Drug Resistance In Nigeria: A Mini Review. BIMA JOURNAL OF SCIENCE AND TECHNOLOGY (2536-6041), 8(3A), 171-188. https://doi.org/10.56892/bima.v8i3.775