ANTIBACTERIAL AND PHYTOCHEMICAL STUDIES OF Pteriocarpus erinaceus CRUDE EXTRACTS AGAINST DIARRHOEAGENIC Esherichia coli

Authors

  • MUHAMMAD, I. L. Department of Microbiology, I.B.B. University, Lapai, Niger state.
  • MUHAMMAD, R. G., Department of Biological Sciences, I.B.B. University, Lapai, Niger state.
  • KASSIM, J. Z. Department of Microbiology, I.B.B. University, Lapai, Niger state.
  • MOHAMMED, A. Department of Microbiology, I.B.B. University, Lapai, Niger state.
  • BABA, J., Department of Microbiology, I.B.B. University, Lapai, Niger state.
  • DADI-MAMUD, N. J. Department of Biological Sciences, I.B.B. University, Lapai, Niger state.
  • AMUZAT, A. O. Department of Biochemistry, I. B. B. University, Lapai,Niger State.

Keywords:

Diarrhoea, Antibacterial, Extract, Phytochemical, Ptericarpus erinaceus

Abstract

The study was carried out to determine the antibacterial and phytochemical studies of
Ptericarpus erinaceus extracts. The antibacterial assay was conducted using agar well diffusion
method. The phytochemical screening was conducted using standard qualitative methods. The
phytochemical screening of Ptericarpuserinaceus leaf extracts commonly contained alkaloids,
flavonoids and steroids, while stem-bark extracts commonly indicated the presence of
anthraquinones, glycosides, saponins and steroids. The bacteriaused were ten isolates
(Escherichia coli) isolated from diarrhoeic stool of children 0-5 years. The result of Ptericarpus
erinaceus crude leaf extracts showed appreciable inhibitory effect on all test isolates at 0.5-2.0
mg/ml concentration with zones of inhibition ranging from 8.00mm-22.00mm, while the entire
isolates were resistance to hexane leaf extract. The stem-bark extracts inhibited the entire isolates
at 0.5-2.0mg/ml concentration with zones of inhibition ranged between 8.00-30.00mm.The
results has justified their utilization by the traditional medicine practioners for the treatment of
ailments associated with the test isolates.

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Published

2020-12-13

How to Cite

MUHAMMAD, I. L., MUHAMMAD, R. G., KASSIM, J. Z., MOHAMMED, A., BABA, J., DADI-MAMUD, N. J., & AMUZAT, A. O. (2020). ANTIBACTERIAL AND PHYTOCHEMICAL STUDIES OF Pteriocarpus erinaceus CRUDE EXTRACTS AGAINST DIARRHOEAGENIC Esherichia coli. BIMA JOURNAL OF SCIENCE AND TECHNOLOGY (2536-6041), 4(02), 66-76. Retrieved from http://journals.gjbeacademia.com/index.php/bimajst/article/view/208

Issue

Vol. 4 No. 02 (2020): Vol. 4 No. 2 December 2020

Section

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